Job Description

A Bioinformatics Research Scientist position is immediately available under the supervision of Dr. Zhaoming Wang in the Department of Epidemiology and Cancer Control at St. Jude Children's Research Hospital. Wang Lab is seeking a talented and highly motivated data scientist to apply established and innovative approaches towards analyzing multi-omics data to discover potential biomarkers for risk of chronic health conditions including second cancers among long-term survivors of childhood cancer. In addition to large-scale molecular profiling data encompassing genome, epigenome, and transcriptome, we also have access to rich longitudinal clinical data from the two largest cohorts of childhood cancer survivors: St. Jude Lifetime Cohort and Childhood Cancer Survivor Study.

Strong expertise in R and/or Python programming is required. Extensive working experience in next-generation sequencing analysis and domain knowledge in one or more of bioinformatics, biostatistics and genetic/molecular epidemiology are highly desired. The ability to work independently and in a team-setting (multi-tasking and effective communications) is also essential.

The Wang Lab is currently focused on cancer genetics (pediatric cancers, subsequent adult cancers), aging biomarkers (telomere, epigenetic age, clonal hematopoiesis), and multi-omics integrative analysis (including single-cell approaches).

Job Responsibilities:

• Work closely with Dr. Wang and others with the overarching goal of contributing to the clinical research by melding multi-omics data with clinical/phenotypic data for discoveries in the area of precision preventive medicine for survivorship care.
• Contribute to multi-omics data management and primary sequencing data analysis by setting up/improving automation pipeline with established computational methods.
• Lead the development of analytical workflows (secondary analyses) for assigned research projects.
• Learn new bioinformatics techniques for data mining in molecular phenotyping (e.g., deconvolution analysis, mosaicism detection, HLA imputation)
• Contribute to the preparation and submission of manuscripts for publication.
• Present to collaborators and team members to report scientific discoveries and educate researchers about relevant methods, software or scientific results.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.

Minimum Education and/or Training:

• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
• Master's degree or PhD preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
• Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience.
• Experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Bioinformatics Research Scientist - Dr. Zhaoming Wang.

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Job Tags

Full time, Work experience placement, Immediate start,

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